Molecular Fingerprinting of Mycobacterium abscessus Strains in a Cohort of Pediatric Cystic Fibrosis Patients
- 1 May 2012
- journal article
- Published by American Society for Microbiology in Journal of Clinical Microbiology
- Vol. 50 (5), 1758-1761
- https://doi.org/10.1128/jcm.00155-12
Abstract
Forty-one Mycobacterium abscessus complex isolates from 17 pediatric cystic fibrosis (CF) patients were typed using a novel variable-number tandem repeat (VNTR) scheme and an automated repetitive-PCR (rep-PCR) system. Both VNTR and rep-PCR typing methods differentiate between members of the M. abscessus complex. The isolates from individual patients are indistinguishable, and the data strongly suggest that individual CF patients are persistently infected with one strain and also suggests that different CF patients can harbor the same strain.Keywords
This publication has 16 references indexed in Scilit:
- The use of a two-gene sequencing approach to accurately distinguish between the species within the Mycobacterium abscessus complex and Mycobacterium chelonaeEuropean Journal of Clinical Microbiology & Infectious Diseases, 2012
- Efficient Differentiation of Mycobacterium abscessus Complex Isolates to the Species Level by a Novel PCR-Based Variable-Number Tandem-Repeat AssayJournal of Clinical Microbiology, 2011
- Multicenter Study of Prevalence of Nontuberculous Mycobacteria in Patients with Cystic Fibrosis in FranceJournal of Clinical Microbiology, 2009
- Cohort Study of Molecular Identification and Typing of Mycobacterium abscessus, Mycobacterium massiliense , and Mycobacterium bolletiiJournal of Clinical Microbiology, 2009
- Outbreak of Mycobacterium massiliense Infection Associated with Intramuscular InjectionsJournal of Clinical Microbiology, 2007
- rpoB gene sequence-based characterization of emerging non-tuberculous mycobacteria with descriptions of Mycobacterium bolletii sp. nov., Mycobacterium phocaicum sp. nov. and Mycobacterium aubagnense sp. nov.International Journal of Systematic and Evolutionary Microbiology, 2006
- Age-Related Prevalence and Distribution of Nontuberculous Mycobacterial Species among Patients with Cystic FibrosisJournal of Clinical Microbiology, 2005
- Mycobacterium abscessus and Other Nontuberculous Mycobacteria: Evolving Respiratory Pathogens in Cystic Fibrosis: A Case Report and ReviewSouthern Medical Journal, 2005
- Microbial DNA Typing by Automated Repetitive-Sequence-Based PCRJournal of Clinical Microbiology, 2005
- rpoB -Based Identification of Nonpigmented and Late-Pigmenting Rapidly Growing MycobacteriaJournal of Clinical Microbiology, 2003