Amputation after Development of Collateral Circulation:An Arteriographic Study in Rabbits
- 1 January 1978
- journal article
- research article
- Published by Medical Journals Sweden AB in Acta Orthopaedica
- Vol. 49 (6), 557-564
- https://doi.org/10.3109/17453677808993238
Abstract
The vascular changes in the amputation stump after amputation on an extremity which is vascularized by collaterals were studied by arteriography in adult rabbits. Amputation on the eras immediately after ligature of the femoral artery caused a retardation in the development of collaterals and a protracted vasoconstriction in the amputation stump. Osseous plugging of the medullary cavity in the amputation stump counteracted the vasoconstriction, and the development of collaterals was improved. When amputation on the crus was performed 3–6 days after ligature of the femoral artery, immediate function of the collaterals and a rapid dilatation of the arteries in the below knee amputation stump were seen, and 3–4 weeks postoperatively arteriovenous shunts developed in the stump. Amputation 7–10 weeks after ligature of the artery involved a more pronounced shunt development in the amputation stump. After amputation on the femur only slight differences were observed in the development of collaterals and the vascularization in the amputation stump compared with findings after amputation on the crus.Keywords
This publication has 6 references indexed in Scilit:
- Muscle blood flow after amputation with special reference to the influence of the amputation level: Assessed by 133 xenon and histamine an animal experimentActa Orthopaedica, 1977
- Muscle Blood Flow after Amputation with Special Reference to the Influence of Osseous Plugging of the Medullary Cavity Assessed by 133 Xenon and Histamine an Animal ExperimentActa Orthopaedica, 1976
- Healing of Amputation Stumps, with Special Reference to Vascularity and BoneActa Orthopaedica, 1966
- CONTRALATERAL VASOCONSTRICTION IN THE HIND LIMB OF THE RAT AND RABBIT1958
- COLLATERAL RESISTANCE IN LIMBS WITH ARTERIAL OBSTRUCTION - SPONTANEOUS CHANGES AND EFFECTS OF SYMPATHECTOMY1951
- Arterial spasm an experimental studyBritish Journal of Surgery, 1942