The Acidic Microclimate in Poly(lactide-co-glycolide) Microspheres Stabilizes Camptothecins
- 1 January 1999
- journal article
- Published by Springer Science and Business Media LLC in Pharmaceutical Research
- Vol. 16 (2), 241-248
- https://doi.org/10.1023/a:1018876308346
Abstract
Purpose. The camptothecin (CPT) analogue, 10-hydroxycamptothecin (10-HCPT) has been shown previously to remain in its acid-stable (and active) lactone form when encapsulated in...Keywords
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