Cardiovascular Safety of Febuxostat or Allopurinol in Patients with Gout
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- 29 March 2018
- journal article
- research article
- Published by Massachusetts Medical Society in The New England Journal of Medicine
- Vol. 378 (13), 1200-1210
- https://doi.org/10.1056/nejmoa1710895
Abstract
Cardiovascular risk is increased in patients with gout. We compared cardiovascular outcomes associated with febuxostat, a nonpurine xanthine oxidase inhibitor, with those associated with allopurinol, a purine base analogue xanthine oxidase inhibitor, in patients with gout and cardiovascular disease.Keywords
Funding Information
- Takeda Pharmaceuticals U.S.A.
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