One-pot Synthesis of Penta- and Hepta-saccharides from Monomeric Mannose Building Blocks Using the Principles of Orthogonality and Reactivity Tuning

Abstract

Employment of the butane-2,3-diacetal protecting group allowed the reactivity tuning of glycosyl fluorides in the one-pot sequential glycosidation of up to five different components affording both linear and branched penta- and heptasaccharides.