Brachial-ankle vs carotid-femoral pulse wave velocity as a determinant of cardiovascular structure and function
- 28 June 2007
- journal article
- research article
- Published by Springer Science and Business Media LLC in Journal of Human Hypertension
- Vol. 22 (1), 24-31
- https://doi.org/10.1038/sj.jhh.1002259
Abstract
Carotid-femoral pulse wave velocity (cf-PWV) is a validated marker of arterial stiffening over the central arteries. Brachial-ankle pulse wave velocity (ba-PWV) integrates the mechanical properties from both the central and peripheral arteries and may be more representative than cf-PWV as arterial load for left ventricle (LV). We compared ba-PWV with cf-PWV for the association of cardiovascular structure and function in 320 subjects with various degrees of abnormality in cardiac structure and function. ba-PWV (by oscillometric technique) and cf-PWV (by tonometric technique) were measured simultaneously, and were highly correlated (r=0.79, Pr=0.29 vs r=0.22, P=0.0219). While ba-PWV and cf-PWV were similarly significantly correlated with LV end-systolic elastance and mitral E/A ratio, ba-PWV had better correlation with isovolumic relaxation constant (r=0.34 vs r=0.27, P=0.0202) than cf-PWV. In addition, the correlation was also significantly stronger with ba-PWV than with cf-PWV for other indices of arterial stiffness, including carotid incremental modulus (r=0.59 vs 0.50, P=0.0013), effective arterial elastance (r=0.41 vs r=0.33, P=0.0081) and carotid augmentation index (r=0.38 vs r=0.32, P=0.0368). In conclusion, ba-PWV correlates better with LV mass and diastolic function and other indices of arterial function than cf-PWV, probably because ba-PWV encompasses a greater territory of arterial tree than cf-PWV.Keywords
This publication has 36 references indexed in Scilit:
- Relation Between Renal Function Within the Normal Range and Central and Peripheral Arterial Stiffness in HypertensionHypertension, 2006
- Ventricular Arterial StiffeningHypertension, 2005
- Stiffness of Capacitive and Conduit ArteriesHypertension, 2005
- Combined use of brachial-ankle pulse wave velocity and ankle-brachial index for fast assessment of arteriosclerosis and atherosclerosis in a communityInternational Journal of Cardiology, 2005
- Changes in Arterial Stiffness and Wave Reflection With Advancing Age in Healthy Men and WomenHypertension, 2004
- Volume Status and Blood Pressure During Long-Term HemodialysisHypertension, 2003
- Influences of age and gender on results of noninvasive brachial–ankle pulse wave velocity measurement—a survey of 12 517 subjectsAtherosclerosis, 2003
- Validation of Carotid Artery Tonometry as a Means of Estimating Augmentation Index of Ascending Aortic PressureHypertension, 1996
- Noninvasive Pulse Wave Analysis for the Early Detection of Vascular DiseaseHypertension, 1995
- Standardization of M-mode echocardiographic left ventricular anatomic measurementsJournal of the American College of Cardiology, 1984