Effects of Rhus coriaria L. (Anacardiaceae) on lipid peroxidation and free radical scavenging activity
- 23 January 2004
- journal article
- research article
- Published by Wiley in Phytotherapy Research
- Vol. 18 (1), 84-86
- https://doi.org/10.1002/ptr.1228
Abstract
In order to evaluate the antioxidant potential of Rhus coriaria L. (Anacardiaceae), a well-known spice, the methanolic extract (water-soluble part) was prepared and investigated using free radical-generating systems in vitro. The IC50 value of the extract for lipid peroxidation was estimated as 1200 µg/mL in the Fe+2-ascorbate system while those for superoxide-scavenging activity in the xanthine-xanthine oxidase method and hydroxyl radical scavenging activity in the deoxyribose decomposition method were 282.92 µg/mL and 3850 µg/mL, respectively. These data suggest that the methanolic extracts of Rhus coriaria L. fruits have considerable antioxidant activity against free radicals and lipid peroxidation in vitro, a fact that may encourage in vivo studies. Copyright © 2004 John Wiley & Sons, Ltd.Keywords
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