What is systems biology?
Open Access
- 1 January 2010
- journal article
- Published by Frontiers Media SA in Frontiers in Physiology
Abstract
Systems biology is increasingly popular, but to many biologists it remains unclear what this new discipline actually encompasses. This brief personal perspective starts by outlining the asthetic qualities that motivate systems biologists, discusses which activities do not belong to the core of systems biology, and finally explores the crucial link with synthetic biology. It concludes by attempting to define systems biology as the research endeavor that aims at providing the scientific foundation for successful synthetic biology.Keywords
This publication has 30 references indexed in Scilit:
- Systems biology approaches to bioremediationCurrent Opinion in Biotechnology, 2008
- Reconstruction of biochemical networks in microorganismsNature Reviews Microbiology, 2008
- Synthetic biology through biomolecular design and engineeringCurrent Opinion in Structural Biology, 2008
- Systems Biology and Artificial Life: Towards Predictive Modeling of Biological SystemsArtificial Life, 2008
- Putting the Systems Back into Systems BiologyPerspectives in Biology and Medicine, 2006
- Foundations for engineering biologyNature, 2005
- Systems Biology and New Technologies Enable Predictive and Preventative MedicineScience, 2004
- Using a Quantitative Blueprint to Reprogram the Dynamics of the Flagella Gene NetworkCell, 2004
- Ordering Genes in a Flagella Pathway by Analysis of Expression Kinetics from Living BacteriaScience, 2001
- A synthetic oscillatory network of transcriptional regulatorsNature, 2000