A new noninvasive finger sensor (NICCI system) for cardiac output monitoring

Abstract

BACKGROUND The new noninvasive finger sensor system NICCI (Getinge; Gothenburg, Sweden) allows continuous cardiac output monitoring. We aimed to investigate its cardiac output measurement performance. OBJECTIVE(S) To investigate the NICCI system's cardiac output measurement performance. DESIGN Prospective method comparison study. SETTING University Medical Center Hamburg-Eppendorf, Hamburg, Germany. PATIENTS Fifty-one patients after cardiac surgery. MAIN OUTCOME MEASURES We performed a method comparison study in 51 patients after cardiac surgery to compare NICCI cardiac output (CO_NICCI) and NICCI cardiac output calibrated to pulmonary artery thermodilution cardiac output measurement (CO_NICCI-CAL) with pulmonary artery thermodilution cardiac output (CO_PAT). As a secondary analysis we also compared CNAP cardiac output (CO_CNAP) and externally calibrated CNAP cardiac output (CO_CNAP-CAL) with CO_PAT. RESULTS We analysed 299 cardiac output measurement pairs. The mean of the differences (95% limits of agreement) between CO_NICCI and CO_PAT was 0.6 (−1.8 to 3.1) l min⁻¹ with a percentage error of 48%. The mean of the differences between CO_NICCI-CAL and CO_PAT was −0.4 (−1.9 to 1.1) l min⁻¹ with a percentage error of 29%. The mean of the differences between CO_CNAP and CO_PAT was 1.0 (−1.8 to 3.8) l min⁻¹ with a percentage error of 53%. The mean of the differences between CO_CNAP-CAL and CO_PAT was −0.2 (−2.0 to 1.6) l min⁻¹ with a percentage error of 35%. CONCLUSION The agreement between CO_NICCI and CO_PAT is not clinically acceptable. TRIAL REGISTRATION The study was registered in the German Clinical Trial Register (DRKS00023189) after inclusion of the first patient on October 2, 2020.