Intraneural perineurioma of the common peroneal nerve
- 1 May 2001
- journal article
- case report
- Published by Journal of Neurosurgery Publishing Group (JNSPG) in Journal of Neurosurgery
- Vol. 94 (5), 811-815
- https://doi.org/10.3171/jns.2001.94.5.0811
Abstract
Intraneural perineurioma, or localized hypertrophic mononeuropathy (LHM), is a focal lesion that produces a slowly progressive mononeuropathy in a peripheral nerve. The authors describe the clinical presentation, magnetic resonance (MR) neurography characteristics, and pathological characteristics of a perineurioma involving the peroneal nerve. Although there has been much debate surrounding the cause of this lesion, a literature review supports the argument that this is a neoplastic lesion, best referred to as intraneural perineurioma. Surgical management includes excision to prevent progression of palsy and placement of a nerve graft if clinically indicated. A 28-year-old woman presented with a 2-year history of progressive painless right peroneal nerve palsy. Magnetic resonance neurography revealed a right common peroneal nerve mass. At surgery, the mass was easily excised, leaving significant nerve fascicles intact. Intraoperative biopsy was not performed nor was a nerve graft placed. Pathological investigation demonstrated onion bulb-shaped whorls consistent with the appearance of intraneural perineurioma; immunochemical analysis confirmed the diagnosis. A review of the literature supports the argument that perineurioma, or LHM, is a neoplastic process, making "intraneural perineurioma" the most appropriate name. The authors also demonstrate the utility of MR neurography in the identification isolated nerve tumors and review the surgical management of this lesion.This publication has 16 references indexed in Scilit:
- Soft-tissue PerineuriomaThe American Journal of Surgical Pathology, 1997
- Intratemporal Facial Nerve PerineuriomaThe Laryngoscope, 1996
- Perineurial cell hypertrophic mononeuropathy manifesting as carpal tunnel syndromeMuscle & Nerve, 1992
- Perineurioma: An Uncommon Soft Tissue Neoplasm Distinct From Localized Hypertrophic Neuropathy and NeurofibromaThe American Journal of Surgical Pathology, 1992
- Immunohistochemical Detection of Epithelial Membrane Antigen in Normal Perineurial Cells and PerineuriomaThe American Journal of Surgical Pathology, 1988
- Localized Hypertrophic Mononeuropathy Involving the Tibial NerveNeurosurgery, 1988
- Localized hypertrophic mononeuropathy involving the tibial nerveNeurosurgery, 1988
- Perineurioma: A Benign Peripheral Nerve TumorNeurosurgery, 1986
- Perineurioma as the cause of localized hypertrophic neuropathyMuscle & Nerve, 1980
- Névrite interstitielle hypertrophique monosymptomatiqueJournal of the Neurological Sciences, 1964