Coronary Arteries of Cardiac Patients Are Hyperreactive and Contain Stores of Amines: A Mechanism for Coronary Spasm
- 30 March 1984
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 223 (4643), 1435-1437
- https://doi.org/10.1126/science.6701530
Abstract
Coronary arteries from hearts of cardiac patients contain significantly higher concentrations of histamine than do those from noncardiac patients. The coronary vessels of cardiac patients are also hyperresponsive to histamine and serotonin. These differences between groups of patients suggest an explanation for coronary artery spasm in heart disease.This publication has 12 references indexed in Scilit:
- Coronary Artery Spasm Induced in Atherosclerotic Miniature SwineScience, 1983
- Coronary-Artery Spasm and Myocardial InfarctionNew England Journal of Medicine, 1983
- Provocation of coronary artery spasm by the cold pressor test. Hemodynamic, arteriographic and quantitative angiographic observations.Cell Metabolism, 1980
- Simple method for the simultaneous determination of noradrenaline, dopamine and serotonin by stepwise elution from a short column of weak cation-exchange resinJournal of Chromatography A, 1979
- Coronary artery vasospasm: the likely immediated cause of acute myocardial infarction.Heart, 1979
- Coronary Vasospasm as a Possible Cause of Myocardial InfarctionNew England Journal of Medicine, 1978
- Norepinephrine in Chronic Paranoid Schizophrenia: Above-Normal Levels in Limbic ForebrainScience, 1978
- Levels of serotonin bound to platelets and free in plasma in jugular and forearm venous blood as determined by a fluorescent-OPT (orthophthalaldehyde) assayClinica Chimica Acta; International Journal of Clinical Chemistry, 1975
- Peri‐arterial mast cells in coronary atheroma and thrombosisThe Journal of Pathology and Bacteriology, 1958
- Mast Cells in the Circulatory System of ManCirculation, 1957