Meta-analysis of the Therapeutic Effect of Hepatectomy Versus Radiofrequency Ablation for the Treatment of Hepatocellular Carcinoma
- 1 June 2010
- journal article
- research article
- Published by Ovid Technologies (Wolters Kluwer Health) in Surgical Laparoscopy, Endoscopy & Percutaneous Techniques
- Vol. 20 (3), 130-140
- https://doi.org/10.1097/sle.0b013e3181d823df
Abstract
Surgical resection has been considered to be the best treatment for hepatocellular carcinoma (HCC). However, in recent years, there has been growing interest in the therapy of radiofrequency ablation (RFA). This meta-analysis is to evaluate the therapeutic effect of those 2 therapeutic methods. Outcomes evaluated were death rate, complications, survival rates, recurrence-free survival rates, and recurrence. Primary authors were contacted to retrieve further information if necessary. There is no significant difference in death rates of the treatment of HCC in the groups of hepatectomy and RFA, although the recurrence of HCC may be lower in the hepatectomy group. In the group of RFA, the recurrence rate in the previous site was higher but was lower in the new area, whereas it seems equal in the extrahepatic area. RFA may have comparable results with surgical resection in patients in the therapeutic effect of ablation for the treatment of HCC, if recurrence of HCC after RFA could be timely detected and effectively treated.Keywords
This publication has 44 references indexed in Scilit:
- Surgical resection versus radiofrequency ablation for small hepatocellular carcinomas within the Milan criteriaJournal of Hepato-Biliary-Pancreatic Surgery, 2009
- Expanding transplant criteria for hepatocellular carcinoma: Small steps down a long roadHepatology, 2009
- Meta-analysis of the need for nasogastric or nasojejunal decompression after gastrectomy for gastric cancerBritish Journal of Surgery, 2008
- Two Hundred Liver Hanging Maneuvers for Major HepatectomyAnnals of Surgery, 2007
- Implication of Frequent Local Ablation Therapy for Intrahepatic Recurrence in Prolonged Survival of Patients With Hepatocellular Carcinoma Undergoing Hepatic ResectionAnnals of Surgery, 2006
- Radiofrequency ablation versus surgical resection for single nodule hepatocellular carcinoma: Long‐term outcomesHPB, 2005
- Survival and recurrences after hepatic resection or radiofrequency for hepatocellular carcinoma in cirrhotic patients: a multivariate analysisJournal of Gastrointestinal Surgery, 2005
- Hepatocellular carcinoma: is current therapy really altering outcome?Gut, 2002
- Clinical Management of Hepatocellular Carcinoma. Conclusions of the Barcelona-2000 EASL ConferenceJournal of Hepatology, 2001
- Ultrasound-guided radiofrequency thermal ablation of liver tumors: percutaneous, laparoscopic, and open surgical approachesJournal of Gastrointestinal Surgery, 2001