Relationship of genotypes of hepatitis B virus to mutations, disease progression and response to antiviral therapy
- 14 July 2005
- journal article
- review article
- Published by Wiley in Journal of Viral Hepatitis
- Vol. 12 (5), 456-464
- https://doi.org/10.1111/j.1365-2893.2005.00624.x
Abstract
Phylogenetic analysis has led to the classification of hepatitis B virus into eight genotypes, designated A to H. The genotypes have differences in biological properties and show heterogeneity in their global distribution. These attributes of the genotypes may account not only for differences in the prevalence of hepatitis B virus mutants in various geographic regions, but also be responsible for differences in the clinical outcome and response to antiviral treatment in different population groups.Keywords
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