Molecular evolution of the reactive oxygen-generating NADPH oxidase (Nox/Duox) family of enzymes
Open Access
- 6 July 2007
- journal article
- Published by Springer Science and Business Media LLC in BMC Evolutionary Biology
- Vol. 7 (1), 109
- https://doi.org/10.1186/1471-2148-7-109
Abstract
NADPH-oxidases (Nox) and the related Dual oxidases (Duox) play varied biological and pathological roles via regulated generation of reactive oxygen species (ROS). Members of the Nox/Duox family have been identified in a wide variety of organisms, including mammals, nematodes, fruit fly, green plants, fungi, and slime molds; however, little is known about the molecular evolutionary history of these enzymes.Keywords
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