Biospecimen Reporting for Improved Study Quality
- 1 March 2011
- journal article
- research article
- Published by Mary Ann Liebert Inc in Biopreservation and Biobanking
- Vol. 9 (1), 57-70
- https://doi.org/10.1089/bio.2010.0036
Abstract
Human biospecimens are subject to a number of different collection, processing, and storage factors that can significantly alter their molecular composition and consistency. These biospecimen preanalytical factors, in turn, influence experimental outcomes and the ability to reproduce scientific results. Currently, the extent and type of information specific to the biospecimen preanalytical conditions reported in scientific publications and regulatory submissions varies widely. To improve the quality of research utilizing human tissues, it is critical that information regarding the handling of biospecimens be reported in a thorough, accurate, and standardized manner. The Biospecimen Reporting for Improved Study Quality recommendations outlined herein are intended to apply to any study in which human biospecimens are used. The purpose of reporting these details is to supply others, from researchers to regulators, with more consistent and standardized information to better evaluate, interpret, compare, and reproduce the experimental results. The Biospecimen Reporting for Improved Study Quality guidelines are proposed as an important and timely resource tool to strengthen communication and publications around biospecimen-related research and help reassure patient contributors and the advocacy community that the contributions are valued and respected.Keywords
This publication has 85 references indexed in Scilit:
- Sources of Bias in Specimens for Research About Molecular Markers for CancerJournal of Clinical Oncology, 2010
- 2009 Biospecimen Research Network Symposium: Advancing Cancer Research through Biospecimen ScienceCancer Research, 2009
- Tissue is alive: New technologies are needed to address the problems of protein biomarker pre‐analytical variabilityProteomics – Clinical Applications, 2009
- Informed consent in biobank research: A deliberative approach to the debateSocial Science & Medicine (1982), 2009
- A Portrait of Tissue Phosphoprotein Stability in the Clinical Tissue Procurement ProcessMolecular & Cellular Proteomics, 2008
- The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement: guidelines for reporting observational studiesJournal of Clinical Epidemiology, 2008
- Effects of Blood Collection Conditions on Ovarian Cancer Serum MarkersPLOS ONE, 2007
- An exfoliation and enrichment strategy results in improved transcriptional profiles when compared to matched formalin fixed samplesBMC Clinical Pathology, 2007
- Successful Application of Microarray Technology to Microdissected Formalin-Fixed, Paraffin-Embedded TissueThe Journal of Molecular Diagnostics, 2007
- Biobanking of fresh frozen tissue: RNA is stable in nonfixed surgical specimensLaboratory Investigation, 2006