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K-252a, a potent inhibitor of protein kinase C from microbial origin.
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K-252a, a potent inhibitor of protein kinase C from microbial origin.
K-252a, a potent inhibitor of protein kinase C from microbial origin.
HK
Hiroshi Kase
Hiroshi Kase
KI
Kazuyuki Iwahashi
Kazuyuki Iwahashi
YM
Yuzuru Matsuda
Yuzuru Matsuda
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1 January 1986
journal article
Published by
Japan Antibiotics Research Association
in
The Journal of Antibiotics
Vol. 39
(8)
,
1059-1065
https://doi.org/10.7164/antibiotics.39.1059
Abstract
K-252a, a metabolite isolated from the culture broth of Nocardiopsis sp. K-252a, was found to exhibit an extremely potent inhibitory activity on protein kinase C. The IC50 value was 32.9 nM.
Keywords
PROTEIN KINASE
252A
EXTREMELY
POTENT INHIBITOR
IC50
NOCARDIOPSIS
METABOLITE
INHIBITORY
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Cited by 233 articles