Matrix Effect-Free Analytical Methods for Determination of Perfluorinated Carboxylic Acids in Environmental Matrixes
- 3 September 2005
- journal article
- research article
- Published by American Chemical Society (ACS) in Analytical Chemistry
- Vol. 77 (19), 6353-6358
- https://doi.org/10.1021/ac0508090
Abstract
Perfluorocarboxylic acids (PFCAs) are persistent chemicals that have been found widely in the environment. Their accurate determination in environmental matrixes, particularly soil, sediment, and sludge, at low levels presents significant analytical challenges. The commercialization of electrospray interfaces for liquid chromatography−mass spectrometric analysis facilitated analysis of PFCAs at low levels, but issues with quantitative analysis due to matrix suppression or enhancement still persist. The methods described in this study utilize simple and rapid sample purification procedures to remove matrix components sufficiently so that errors due to coeluting matrix peaks are negligible and recoveries of PFCAs are consistently and reproducibly quantitative. Extracts from solid samples (soil and sediment) and liquid bacterial sludge are purified using dispersive solid-phase extraction. Recovery values generally are in the 70−120% range, with limits of quantitation of 1 ppb. The method utilizes an extraction solvent previously shown to release and recover aged residues of PFCAs. A confirmatory method using two precursor to product ions is also provided and demonstrated.This publication has 11 references indexed in Scilit:
- Quantitative Determination of Perfluorochemicals in Sediments and Domestic SludgeEnvironmental Science & Technology, 2005
- Analysis of Perfluorinated Acids at Parts-Per-Quadrillion Levels in Seawater Using Liquid Chromatography-Tandem Mass SpectrometryEnvironmental Science & Technology, 2004
- Concentrations of perfluorooctane sulfonate (PFOS) and perfluorooctanoic acid (PFOA) in vacuum cleaner dust collected in Japanese homesPublished by Royal Society of Chemistry (RSC) ,2003
- Occurrence and persistence of perfluorooctanesulfonate and other perfluorinated surfactants in groundwater at a fire-training area at Wurtsmith Air Force Base, Michigan, USAElectronic supplementary information (ESI) available: Map of location of Wurtsmith Air Force Base, Oscoda, MI and surrounding states. See http://www.rsc.org/suppdata/em/b2/b212497a/Journal of Environmental Monitoring, 2003
- Peer Reviewed: Perfluorochemical Surfactants in the EnvironmentPublished by American Chemical Society (ACS) ,2002
- Quantitative Characterization of Trace Levels of PFOS and PFOA in the Tennessee RiverEnvironmental Science & Technology, 2002
- Monitoring Perfluorinated Surfactants in Biota and Surface Water Samples Following an Accidental Release of Fire-Fighting Foam into Etobicoke CreekEnvironmental Science & Technology, 2001
- Determination of Perfluorinated Surfactants in Surface Water Samples by Two Independent Analytical Techniques: Liquid Chromatography/Tandem Mass Spectrometry and 19F NMRAnalytical Chemistry, 2001
- Determination of Perfluorocarboxylates in Groundwater Impacted by Fire-Fighting ActivityEnvironmental Science & Technology, 1999
- Evidence that there are Two Forms of Fluoride in Human SerumNature, 1968