High Hemocyte Load Is Associated with Increased Resistance against Parasitoids in Drosophila suzukii, a Relative of D. melanogaster
Open Access
- 17 April 2012
- journal article
- research article
- Published by Public Library of Science (PLoS) in PLOS ONE
- Vol. 7 (4), e34721
- https://doi.org/10.1371/journal.pone.0034721
Abstract
Among the most common parasites of Drosophila in nature are parasitoid wasps, which lay their eggs in fly larvae and pupae. D. melanogaster larvae can mount a cellular immune response against wasp eggs, but female wasps inject venom along with their eggs to block this immune response. Genetic variation in flies for immune resistance against wasps and genetic variation in wasps for virulence against flies largely determines the outcome of any fly-wasp interaction. Interestingly, up to 90% of the variation in fly resistance against wasp parasitism has been linked to a very simple mechanism: flies with increased constitutive blood cell (hemocyte) production are more resistant. However, this relationship has not been tested for Drosophila hosts outside of the melanogaster subgroup, nor has it been tested across a diversity of parasitoid wasp species and strains. We compared hemocyte levels in two fly species from different subgroups, D. melanogaster and D. suzukii, and found that D. suzukii constitutively produces up to five times more hemocytes than D. melanogaster. Using a panel of 24 parasitoid wasp strains representing fifteen species, four families, and multiple virulence strategies, we found that D. suzukii was significantly more resistant to wasp parasitism than D. melanogaster. Thus, our data suggest that the relationship between hemocyte production and wasp resistance is general. However, at least one sympatric wasp species was a highly successful infector of D. suzukii, suggesting specialists can overcome the general resistance afforded to hosts by excessive hemocyte production. Given that D. suzukii is an emerging agricultural pest, identification of the few parasitoid wasps that successfully infect D. suzukii may have value for biocontrol.Keywords
This publication has 60 references indexed in Scilit:
- First records of the potential pest species Drosophila suzukii (Diptera: Drosophilidae) in EuropeJournal of Applied Entomology, 2010
- Cell lineage tracing reveals the plasticity of the hemocyte lineages and of the hematopoietic compartments in Drosophila melanogasterMolecular Immunology, 2010
- Contrasting Infection Strategies in Generalist and Specialist Wasp Parasitoids of Drosophila melanogasterPLoS Pathogens, 2007
- Geographical distributions and host associations of larval parasitoids of frugivorous Drosophilidae in JapanJournal of Natural History, 2007
- The fly Drosophila subobscura: A natural case of innate immunity deficiencyDevelopmental & Comparative Immunology, 2006
- Conversely to its sibling Drosophila melanogaster, D. simulans overcomes the immunosuppressive effects of the parasitoid Asobara citriDevelopmental & Comparative Immunology, 2005
- Drosophila melanogaster Rac2 is necessary for a proper cellular immune responseGenes to Cells, 2005
- Drosophila resistance genes to parasitoids: chromosomal location and linkage analysisProceedings. Biological sciences, 2000
- Evolutionary relationships to parasitism by seven species of the Drosophila melanogaster subgroupBiological Journal of the Linnean Society, 1981
- Alterations in the haemocyte population of Drosophila melanogasterJournal of Morphology, 1957