Cohort study of the association of antibody levels to AMA1, MSP119, MSP3 and GLURP with protection from clinical malaria in Ghanaian children
Open Access
- 29 July 2008
- journal article
- Published by Springer Science and Business Media LLC in Malaria Journal
- Vol. 7 (1), 142
- https://doi.org/10.1186/1475-2875-7-142
Abstract
Antigen-specific antibody-mediated immune responses play an important role in natural protection against clinical malaria, but conflicting estimates of this association have emerged from immuno-epidemiological studies in different geographical settings. This study was aimed at assessing in a standardized manner the relationship between the antibody responses to four malaria vaccine candidate antigens and protection from clinical malaria, in a cohort of Ghanaian children.Keywords
This publication has 54 references indexed in Scilit:
- Humoral Responses toPlasmodium falciparumBlood-Stage Antigens and Association with Incidence of Clinical Malaria in Children Living in an Area of Seasonal Malaria Transmission in Burkina Faso, West AfricaInfection and Immunity, 2008
- In Immunization with Plasmodium falciparum Apical Membrane Antigen 1, the Specificity of Antibodies Depends on the Species ImmunizedInfection and Immunity, 2007
- Correlations between treatment outcome and both anti-MSP119 antibody response and erythrocyte-related genetic factors in Plasmodium falciparum malariaInfection, Genetics and Evolution, 2007
- Target Antigen, Age, and Duration of Antigen Exposure Independently Regulate Immunoglobulin G Subclass Switching in MalariaInfection and Immunity, 2006
- IgG isotype to C-terminal 19 kDa of Plasmodium vivax merozoite surface protein 1 among subjects with different levels of exposure to malaria in BrazilZeitschrift für Parasitenkunde, 2005
- Inhibitory and blocking monoclonal antibody epitopes on merozoite surface protein 1 of the malaria parasite Plasmodium falciparumJournal of Molecular Biology, 2001
- Host Age as a determinant of naturally acquired immunity to Plasmodium falciparumParasitology Today, 1995
- What is clinical malaria? Finding case definitions for field research in highly endemic areasParasitology Today, 1994
- Attributable fraction estimates and case definitions for malaria in endemicStatistics in Medicine, 1994
- Antibodies in falciparum malaria: what matters most, quantity or quality?Memórias do Instituto Oswaldo Cruz, 1992