Muscle biopsy in AIDS and ARC: Analysis of 50 patients
- 1 June 1990
- journal article
- research article
- Published by Wiley in Muscle & Nerve
- Vol. 13 (6), 541-544
- https://doi.org/10.1002/mus.880130611
Abstract
We report a large spectrum of histological muscle abnormalities in 50 homosexual men with AIDS and ARC. We encountered moth‐eaten fibers in 76%, angulated fibers in 76%, type groupings in 62%, type 2 fiber atrophy in 58%, mononuclear endomysial and/or perivascular in filtrates in 36%, necrosis and phagocytosis in 30%, and target fibers in 6%. Two patients showed vasculitis and two others showed perifascicular atrophy. On the whole, 96% of the biopsies showed substantial abnormalities. Muscle involvement in AIDS seems more common than previously suspected.Keywords
This publication has 16 references indexed in Scilit:
- The spectrum of changes on 20 nerve biopsies in patients with HIV infectionMuscle & Nerve, 1989
- Peripheral Neuropathy Associated With Acquired Immunodeficiency SyndromeArchives of Neurology, 1988
- Human immunodeficiency virus—associated myopathy: Analysis of 11 patientsAnnals of Neurology, 1988
- Rheumatic manifestations of human immunodeficiency virus infectionAmerican Journal Of Medicine, 1988
- Subacute Structural Myopathy Associated With Human Immunodeficiency Virus InfectionArchives of Neurology, 1988
- Peripheral neuropathies associated with human immunodeficiency virus infectionAnnals of Neurology, 1988
- Neuromuscular diseases associated with human immunodeficiency virus infectionAnnals of Neurology, 1988
- Myopathy complicating the acquired immune deficiency syndromeMuscle & Nerve, 1987
- Neurological complications of acquired immune deficiency syndrome: Analysis of 50 patientsAnnals of Neurology, 1983