Selective detection of bacterial layers with terahertz plasmonic antennas
Open Access
- 23 October 2012
- journal article
- research article
- Published by Optica Publishing Group in Biomedical Optics Express
- Vol. 3 (11), 2937-2949
- https://doi.org/10.1364/BOE.3.002937
Abstract
Current detection and identification of micro-organisms is based on either rather unspecific rapid microscopy or on more accurate but complex and time-consuming procedures. In a medical context, the determination of the bacteria Gram type is of significant interest. The diagnostic of microbial infection often requires the identification of the microbiological agent responsible for the infection, or at least the identification of its family (Gram type), in a matter of minutes. In this work, we propose to use terahertz frequency range antennas for the enhanced selective detection of bacteria types. Several microorganisms are investigated by terahertz time-domain spectroscopy: a fast, contactless and damage-free investigation method to gain information on the presence and the nature of the microorganisms. We demonstrate that plasmonic antennas enhance the detection sensitivity for bacterial layers and allow the selective recognition of the Gram type of the bacteria.Keywords
This publication has 17 references indexed in Scilit:
- Label-free bacteria detection using evanescent mode of a suspended core terahertz fiberOptics Express, 2012
- Microbial biosensors: A reviewBiosensors and Bioelectronics, 2010
- Scattering efficiency and near field enhancement of active semiconductor plasmonic antennas at terahertz frequenciesOptics Express, 2010
- Understanding SERS of bacteriaJournal of Raman Spectroscopy, 2008
- Nanoscale devices for online dielectric spectroscopy of biological cellsPhysiological Measurement, 2008
- Pathogen detection: A perspective of traditional methods and biosensorsBiosensors and Bioelectronics, 2006
- Comparison of E. coli O157:H7 preparation methods used for detection with surface plasmon resonance sensorSensors and Actuators B: Chemical, 2005
- Thermal switching of the enhanced transmission of terahertz radiation through subwavelength aperturesOptics Letters, 2004
- Biosensors for detection of pathogenic bacteriaBiosensors and Bioelectronics, 1999
- The permeability of the wall fabric of Escherichia coli and Bacillus subtilisJournal of Bacteriology, 1996