Delayed antimicrobial effects of skin disinfection by alcohol
- 1 June 1979
- journal article
- research article
- Published by Cambridge University Press (CUP) in Epidemiology and Infection
- Vol. 82 (3), 497-500
- https://doi.org/10.1017/s0022172400054024
Abstract
SUMMARY: Aqueous suspensions of Staphylococcus aureus were deposited on a Millipore filter and then exposed for a few seconds to 70 % ethyl alcohol. Viable counts of bacteria extracted from the filter immediately after exposure to alcohol, and, in replicate experiments, after a further period of 3 h, showed that the mean immediate reduction of 97·6 % in viable counts after treatment with alcohol was followed by a further mean reduction of 67· 1 % in the further 3 h holding time; the same bacterial suspensions allowed to dry on Millipore filters without exposure to alcohol showed a significantly smaller mean reduction in viable counts (34·3 %) during a further 3 h holding time. These findings support the view that the reported further fall in numbers of bacteria on hands while wearing gloves for 3 h after alcohol disinfection can be explained by sublethal damage to some of the bacteria, from which they can recover only if promptly inoculated on culture medium.This publication has 9 references indexed in Scilit:
- Disinfection of the Skin with Detergent Preparations of Irgasan DP 300 and Other AntisepticsBMJ, 1974
- Preoperative Disinfection of Surgeons' Hands: Use of Alcoholic Solutions and Effects of Gloves on Skin FloraBMJ, 1974
- Use of 4% Chlorhexidine Detergent Solution (Hibiscrub) and Other Methods of Skin DisinfectionBMJ, 1973
- Survival of wound pathogens under different environmental conditionsEpidemiology and Infection, 1968
- Ward floors and other surfaces as reservoirs of hospital infectionEpidemiology and Infection, 1967
- Methods for Disinfection of Hands and Operation SitesBMJ, 1964
- The influence of atmospheric drying on the survival of wound floraEpidemiology and Infection, 1953
- Individual Comparisons by Ranking MethodsBiometrics Bulletin, 1945
- The estimation of the bactericidal power of the bloodEpidemiology and Infection, 1938