Tissue Self-Affinity and Polarized Light Scattering in the Born Approximation: A New Model for Precancer Detection
- 28 September 2006
- journal article
- research article
- Published by American Physical Society (APS) in Physical Review Letters
- Vol. 97 (13), 138102
- https://doi.org/10.1103/physrevlett.97.138102
Abstract
Light scattered from biological tissues can exhibit an inverse power law spectral component. We develop a model based on the Born approximation and von Karman (self-affine) spatial correlation of submicron tissue refractive index to account for this. The model is applied to light scattering spectra obtained from excised esophagi of normal and carcinogen-treated rats. Power law exponents used to fit dysplastic tissue site spectra are significantly smaller than those from normal sites, indicating that changes in tissue self-affinity can serve as a potential biomarker for precancer.This publication has 13 references indexed in Scilit:
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