Dietary protein – its role in satiety, energetics, weight loss and health
Open Access
- 1 August 2012
- journal article
- review article
- Published by Cambridge University Press (CUP) in British Journal of Nutrition
- Vol. 108 (S2), S105-S112
- https://doi.org/10.1017/s0007114512002589
Abstract
Obesity is a serious health problem because of its co-morbidities. The solution, implying weight loss and long-term weight maintenance, is conditional on: (i) sustained satiety despite negative energy balance, (ii) sustained basal energy expenditure despite BW loss due to (iii) a sparing of fat-free mass (FFM), being the main determinant of basal energy expenditure. Dietary protein has been shown to assist with meeting these conditions, since amino acids act on the relevant metabolic targets. This review deals with the effects of different protein diets during BW loss and BW maintenance thereafter. Potential risks of a high protein diet are dealt with. The required daily intake is 0·8–1·2 g/kg BW, implying sustaining the original absolute protein intake and carbohydrate and fat restriction during an energy-restricted diet. The intake of 1·2 g/kg BW is beneficial to body composition and improves blood pressure. A too low absolute protein content of the diet contributes to the risk of BW regain. The success of the so-called ‘low carb’ diet that is usually high in protein can be attributed to the relatively high-protein content per se and not to the relatively lower carbohydrate content. Metabolic syndrome parameters restore, mainly due to BW loss. With the indicated dosage, no kidney problems have been shown in healthy individuals. In conclusion, dietary protein contributes to the treatment of obesity and the metabolic syndrome, by acting on the relevant metabolic targets of satiety and energy expenditure in negative energy balance, thereby preventing a weight cycling effect.Keywords
This publication has 50 references indexed in Scilit:
- Single-Protein Casein and Gelatin Diets Affect Energy Expenditure Similarly but Substrate Balance and Appetite Differently in Adults 1–3Journal of Nutrition, 2009
- Dietary Protein, Weight Loss, and Weight MaintenanceAnnual Review of Nutrition, 2009
- A breakfast with alpha-lactalbumin, gelatin, or gelatin+TRP lowers energy intake at lunch compared with a breakfast with casein, soy, whey, or whey-GMPClinical Nutrition, 2009
- Comparison of 2 diets with either 25% or 10% of energy as casein on energy expenditure, substrate balance, and appetite profileThe American Journal of Clinical Nutrition, 2009
- High protein intake sustains weight maintenance after body weight loss in humansInternational Journal of Obesity, 2003
- Gluttony and thermogenesis revisitedInternational Journal of Obesity, 1999
- Randomized trial on protein vs carbohydrate in ad libitum fat reduced diet for the treatment of obesityInternational Journal of Obesity, 1999
- Diet induced thermogenesis measured over 24h in a respiration chamber: effect of diet compositionInternational Journal of Obesity, 1999
- Obesity in EuropeObesity Research, 1995
- Medical Hazards of ObesityAnnals of Internal Medicine, 1993