Dupuytren's contracture and alcohol.
Open Access
- 1 April 1986
- journal article
- research article
- Published by BMJ in Annals Of The Rheumatic Diseases
- Vol. 45 (4), 304-307
- https://doi.org/10.1136/ard.45.4.304
Abstract
Reported alcohol consumption was quantified and scored by a validated questionnaire administered by an interviewer to 64 patients (10 female) with Dupuytren's contracture (DC) before hand surgery and to 89 controls (44 female) admitted for other hand or foot surgery. Serum urate (SUA), gamma-glutamyl transferase (GGT), and mean red cell volume (MCV) were measured on admission. Thirteen of 54 men with DC reported current daily alcohol intake of 40 g or more compared with one of 45 male controls (p = 0.0001). Two of 10 women with DC (but none of 44 controls) admitted consuming at least 40 g alcohol daily (p = 0.03). MCV was higher in men (but not women) with DC than in controls (p less than 0.0005). Current alcohol consumption score of patients with DC correlated with SUA (r = 0.308, p less than 0.05), MCV (r = 0.44, p less than 0.01), and GGT (r = 0.54, p much less than 0.001) on admission. DC among men is strongly associated with heavy drinking, reflected both in self reporting and haematological data.Keywords
This publication has 23 references indexed in Scilit:
- Alcohol consumption in arthritic patients: clinical and laboratory studies.Annals Of The Rheumatic Diseases, 1985
- Lipid composition and de novo lipid biosynthesis of human palmar fat in Dupuytren's diseaseLipids, 1983
- MEAN CELL VOLUME AND GAMMA-GLUTAMYL-TRANSPEPTIDASE AS MARKERS OF DRINKING IN WORKING MENThe Lancet, 1981
- Familial Dupuytren's contracture with predominantly female expressionBritish Journal of Plastic Surgery, 1979
- Dupuytren's Disease — the Influence Of Occupation and Previous Hand InjuriesThe Hand, 1978
- Morbidity in alcoholics. Evidence for accelerated development of physical disease in womenArchives of Internal Medicine, 1977
- MACROCYTOSIS OF CHRONIC ALCOHOLISMThe Lancet, 1974
- Dupuytren's disease. Its association with abnormal liver function in alcoholism and epilepsyArchives of Internal Medicine, 1972
- Dupuytren's contracture. Its association with alcoholism and cirrhosisArchives of Internal Medicine, 1970
- Thickening and Contraction of the Palmar Fascia (Dupuytren's Contracture) Associated with Alcoholism and Hepatic CirrhosisNew England Journal of Medicine, 1956