A case of suspected familial white sponge nevus of the oral mucosa

Abstract

We report a case of suspected familial white sponge nevus of the oral mucosa. A 38-year-old woman was referred to our department because of white lesions presenting bilaterally on the buccal mucosa. Biopsy of the buccal mucosa revealed epithelial hyperplasia with parakeratosis and a basket-weave-like pattern. Moreover, characteristic eosinophilic perinuclear zones were observed in the vacuolated epithelial cells. On the basis of these findings, white sponge nevus was diagnosed histologically. As similar lesions were found in the oral mucosa of the patient’s two children, these lesions were suspected to be familial white sponge nevus. Currently, these patients are being followed up carefully without any treatment.