Similar bifidogenic effects of prebiotic-supplemented partially hydrolyzed infant formula and breastfeeding on infant gut microbiota
Open Access
- 1 January 2005
- journal article
- Published by Oxford University Press (OUP) in FEMS Immunology & Medical Microbiology
- Vol. 43 (1), 59-65
- https://doi.org/10.1016/j.femsim.2004.07.005
Abstract
The aim of the study was to assess the quantitative and qualitative differences of the gut microbiota in infants. We evaluated gut microbiota at the age of 6 months in 32 infants who were either exclusively breast-fed, formula-fed, nursed by a formula supplemented with prebiotics (a mixture of fructo- and galacto-oligosaccharides) or breast-fed by mothers who had been given probiotics. The Bifidobacterium, Bacteroides, Clostridium and Lactobacillus/Enterococcus microbiota were assessed by the fluorescence in situ hybridization, and Bifidobacterium species were further characterized by PCR. Total number of bifidobacteria was lower among the formula-fed group than in other groups (P= 0.044). Total amounts of the other bacteria were comparable between the groups. The specific Bifidobacterium microbiota composition of the breast-fed infants was achieved in infants receiving prebiotic supplemented formula. This would suggest that early gut Bifidobacterium microbiota can be modified by special diets up to the age of 6 months.Keywords
This publication has 25 references indexed in Scilit:
- Role of probiotics in food hypersensitivityCurrent Opinion in Allergy and Clinical Immunology, 2002
- Supplementation of a bovine milk formula with an oligosaccharide mixture increases counts of faecal bifidobacteria in preterm infantsArchives of Disease in Childhood: Fetal & Neonatal, 2002
- Distinct patterns of neonatal gut microflora in infants in whom atopy was and was not developingJournal of Allergy and Clinical Immunology, 2001
- Analysis of Intestinal Flora Development in Breast-Fed and Formula-Fed Infants by Using Molecular Identification and Detection MethodsJournal of Pediatric Gastroenterology and Nutrition, 2000
- Distribution of Bifidobacterial Species in Human Intestinal Microflora Examined with 16S rRNA-Gene-Targeted Species-Specific PrimersApplied and Environmental Microbiology, 1999
- Developmental microbial ecology of the neonatal gastrointestinal tractThe American Journal of Clinical Nutrition, 1999
- Influences of microbiota on intestinal immune system developmentThe American Journal of Clinical Nutrition, 1999
- Development of Intestinal Microflora in Humans and AnimalsBifidobacteria and Microflora, 1986
- Recent Trends in Research on Intestinal FloraBifidobacteria and Microflora, 1982
- The development of the bacterial flora in normal neonatesJournal of Medical Microbiology, 1981