Index-based Dietary Patterns and the Risk of Prostate Cancer in the NIH-AARP Diet and Health Study
Open Access
- 13 February 2013
- journal article
- research article
- Published by Oxford University Press (OUP) in American Journal of Epidemiology
- Vol. 177 (6), 504-513
- https://doi.org/10.1093/aje/kws261
Abstract
Few studies have investigated the relationship between overall diet and the risk of prostate cancer. We examined the association between 3 diet quality indices—the Healthy Eating Index-2005 (HEI-2005), Alternate Healthy Eating Index-2010 (AHEI-2010), and alternate Mediterranean diet score (aMED)—and prostate cancer risk. At baseline, dietary intake was assessed in a cohort of 293,464 US men in the National Institutes of Health (NIH)-AARP Diet and Health Study. Cox proportional hazards regression was used to estimate hazard ratios. Between 1995 and 2006, we ascertained 23,453 incident cases of prostate cancer, including 2,251 advanced cases and 428 fatal cases. Among men who reported a history of prostate-specific antigen testing, high HEI-2005 and AHEI-2010 scores were associated with lower risk of total prostate cancer (for the highest quintile compared with the lowest, hazard ratio (HR) = 0.92, 95% confidence interval (CI): 0.86, 0.98, P for trend = 0.01; and HR = 0.93, 95% CI: 0.88, 0.99, P for trend = 0.05, respectively). No significant association was observed between aMED score and total prostate cancer or between any of the indices and advanced or fatal prostate cancer, regardless of prostate-specific antigen testing status. In individual component analyses, the fish component of aMED and ω-3 fatty acids component of AHEI-2010 were inversely associated with fatal prostate cancer (HR = 0.79, 95% CI: 0.65, 0.96, and HR = 0.94, 95% CI: 0.90, 0.98, respectively).Keywords
This publication has 41 references indexed in Scilit:
- Adherence to a Low-Risk, Healthy Lifestyle and Risk of Sudden Cardiac Death Among WomenJAMA, 2011
- U.S. Department of Agriculture and U.S. Department of Health and Human Services, Dietary Guidelines for Americans, 2010. 7th Edition, Washington, DC: U.S. Government Printing Office, January 2011Advances in Nutrition: An International Review Journal, 2011
- Diet-Quality Scores and the Risk of Type 2 Diabetes in MenDiabetes Care, 2011
- Dietary Patterns and Prostate Cancer RiskCancer Epidemiology, Biomarkers & Prevention, 2009
- Fish intake and the risk of fatal prostate cancer: findings from a cohort study in JapanPublic Health Nutrition, 2009
- Dietary Patterns Identified Using Factor Analysis and Prostate Cancer Risk: A Case Control Study in Western AustraliaAnnals of Epidemiology, 2008
- Calcium, Dairy Foods, and Risk of Incident and Fatal Prostate Cancer: The NIH-AARP Diet and Health StudyAmerican Journal of Epidemiology, 2007
- 15-lipoxygenase metabolites of γ-linolenic acid/eicosapentaenoic acid suppress growth and arachidonic acid metabolism in human prostatic adenocarcinoma cells: Possible implications of dietary fatty acidsProstaglandins, Leukotrienes & Essential Fatty Acids, 2005
- A Prospective Study of Tomato Products, Lycopene, and Prostate Cancer RiskJNCI Journal of the National Cancer Institute, 2002
- Design and Serendipity in Establishing a Large Cohort with Wide Dietary Intake DistributionsAmerican Journal of Epidemiology, 2001