Identifying Protein Function—A Call for Community Action
Open Access
- 16 March 2004
- journal article
- essay
- Published by Public Library of Science (PLoS) in PLoS Biology
- Vol. 2 (3), e42
- https://doi.org/10.1371/journal.pbio.0020042
Abstract
Functional information is lacking for many of the hypothetical proteins encoded within sequenced genomes. Richard Roberts proposes that a community-based approach might offer an effecient way to fill the function gap.Keywords
This publication has 4 references indexed in Scilit:
- The hemK gene in Escherichia coli encodes the N5-glutamine methyltransferase that modifies peptide release factorsThe EMBO Journal, 2002
- HemK, a class of protein methyl transferase with similarity to DNA methyl transferases, methylates polypeptide chain release factors, and hemK knockout induces defects in translational terminationProceedings of the National Academy of Sciences of the United States of America, 2002
- Life with 6000 GenesScience, 1996
- Cloning and sequencing of a previously unidentified gene that is involved in the biosynthesis of heme in Escherichia coliGene, 1995