Female urethral carcinoma: an analysis of treatment outcome and a plea for a standardized management strategy
- 1 December 1998
- journal article
- research article
- Published by Wiley in British Journal of Urology
- Vol. 82 (6), 835-841
- https://doi.org/10.1046/j.1464-410x.1998.00878.x
Abstract
To evaluate our experience with primary carcinomas of the female urethra, by analysing the impact of tumour variables and treatment on overall, disease-specific, local recurrence- and metastasis-free survival. Between 1958 and 1994, 72 women (median age 60 years, mean 59, range 21–84) with primary urethral carcinoma were identified. They were followed for a median (range) of 85 (0–384) months. The patients were stratified by stage, nodal status, histology, treatment, type of surgery, site of disease, year of diagnosis and smoking habit. In a univariate analysis, stage, nodal status, type of surgery and site of the disease were important factors for survival and recurrence. In a multivariate analysis, primary stage, nodal status and site of disease were independent predictors of survival. Current modalities of treatment are ineffective for local control and survival; new treatment strategies are needed for female urethral cancers.Keywords
This publication has 10 references indexed in Scilit:
- Interactions between outcomes and tumor response to preoperative cisplatin-sensitized radiotherapy in advanced head and neck cancerThe American Journal of Surgery, 1997
- Primary carcinoma of the female urethra results of radiation therapyCancer, 1993
- SURGICAL TREATMENT OF FEMALE URETHRAL CARCINOMAUrologic Clinics of North America, 1992
- A comparison of the roles of surgery and radiation therapy in the management of carcinoma of the female urethraInternational Journal of Radiation Oncology*Biology*Physics, 1991
- Carcinoma of the Female Urethra: A Review of Results with Radiation TherapyJournal of Urology, 1988
- Primary carcinima of female urethraUrology, 1983
- Design and analysis of randomized clinical trials requiring prolonged observation of each patient. II. Analysis and examplesBritish Journal of Cancer, 1977
- Partial likelihoodBiometrika, 1975
- Regression Models and Life‐TablesJournal of the Royal Statistical Society: Series B (Methodological), 1972
- Nonparametric Estimation from Incomplete ObservationsJournal of the American Statistical Association, 1958