Generation of multilayered structures for biomedical applications using a novel tri-needle coaxial device and electrohydrodynamic flow
Open Access
- 22 July 2008
- journal article
- Published by The Royal Society in Journal of The Royal Society Interface
- Vol. 5 (27), 1255-1261
- https://doi.org/10.1098/rsif.2008.0247
Abstract
In this short communication, we describe the scope and flexibility of using a novel device containing three coaxially arranged needles to form a variety of novel morphologies. Different combinations of materials are subjected to controlled flow through the device under the influence of an applied electric field. The resulting electrohydrodynamic flow allows us to prepare double-layered bubbles, porous encapsulated threads and nanocapsules containing three layers. The ability to process such multilayered structures is very significant for biomedical engineering applications, for example, generating capsules for drug delivery, which can provide multistage controlled release.Keywords
This publication has 31 references indexed in Scilit:
- Increasing the nonlinear character of microbubble oscillations at low acoustic pressuresJournal of The Royal Society Interface, 2008
- Tumor specific ultrasound enhanced gene transfer in vivo with novel liposomal bubblesJournal of Controlled Release, 2008
- A dual-functional fibrous scaffold enhances P450 activity of cultured primary rat hepatocytesActa Biomaterialia, 2007
- Novel Electrohydrodynamic Printing of Nanocomposite Biopolymer ScaffoldsJournal of Bioactive and Compatible Polymers, 2007
- Micro- and Nanoparticles via Capillary FlowsAnnual Review of Fluid Mechanics, 2007
- Electrically forced microthreading of highly viscous dielectric liquidsJournal of Electrostatics, 2006
- A novel method for the preparation of biodegradable microspheres for protein drug deliveryJournal of The Royal Society Interface, 2006
- Microintegrating smooth muscle cells into a biodegradable, elastomeric fiber matrixBiomaterials, 2006
- Electrospinning of linear homopolymers of poly(methyl methacrylate): exploring relationships between fiber formation, viscosity, molecular weight and concentration in a good solventPolymer, 2005
- A novel ceramic printing technique based on electrostatic atomization of a suspensionMaterials Research Innovations, 2002