The Companion Dog as a Model for the Longevity Dividend
Open Access
- 4 January 2016
- journal article
- review article
- Published by Cold Spring Harbor Laboratory in Cold Spring Harbor Perspectives in Medicine
- Vol. 6 (1), a026633
- https://doi.org/10.1101/cshperspect.a026633
Abstract
The companion dog is the most phenotypically diverse species on the planet. This enormous variability between breeds extends not only to morphology and behavior but also to longevity and the disorders that affect dogs. There are remarkable overlaps and similarities between the human and canine species. Dogs closely share our human environment, including its many risk factors, and the veterinary infrastructure to manage health in dogs is second only to the medical infrastructure for humans. Distinct breed-based health profiles, along with their well-developed health record system and high overlap with the human environment, make the companion dog an exceptional model to improve understanding of the physiological, social, and economic impacts of the longevity dividend (LD). In this review, we describe what is already known about age-specific patterns of morbidity and mortality in companion dogs, and then explore whether this existing evidence supports the LD. We also discuss some potential limitations to using dogs as models of aging, including the fact that many dogs are euthanized before they have lived out their natural life span. Overall, we conclude that the companion dog offers high potential as a model system that will enable deeper research into the LD than is otherwise possible.Keywords
This publication has 58 references indexed in Scilit:
- Defining healthy aging in older dogs and differentiating healthy aging from diseaseJournal of the American Veterinary Medical Association, 2015
- Long-Term Health Effects of Neutering Dogs: Comparison of Labrador Retrievers with Golden RetrieversPLOS ONE, 2014
- Longevity and mortality of owned dogs in EnglandThe Veterinary Journal, 2013
- Neutering Dogs: Effects on Joint Disorders and Cancers in Golden RetrieversPLOS ONE, 2013
- How dogs know when communication is intended for themDevelopmental Science, 2011
- Mortality in North American Dogs from 1984 to 2004: An Investigation into Age‐, Size‐, and Breed‐Related Causes of DeathJournal of Veterinary Internal Medicine, 2011
- Methods and mortality results of a health survey of purebred dogs in the UKJournal of Small Animal Practice, 2010
- Are functional and demographic senescence genetically independent?Experimental Gerontology, 2006
- Exceptional Longevity in Pet Dogs Is Accompanied by Cancer Resistance and Delayed Onset of Major DiseasesThe Journals of Gerontology: Series A, 2003
- Variation in age at death of dogs of different sexes and breeds.1982