Commercial application of biological control: status and prospects

Abstract
The global market value of control agents used in crop protection and public health is approaching $16 000 million annually, but less than 1% of this market is penetrated by biological control agents (BCAs). This paper examines the suitability of different types of BCA to research and commercialization, bearing in mind the sharply targeted approach employed by much of the industry. Advantages and disadvantages are discussed along with examples of failures and successes with BCAs. Commercialized products described range from specific chemical control agents which have no adverse effects on beneficial organisms to true BCAs such as pheromones, mass-produced bacteria, and predatory mites. From a commercial viewpoint, greatest potential resides with the utilization of bacteria and fungi, particularly for insect control, but registerability (particularly for genetically engineered agents) patentability, reliability and cost-effectiveness must be achieved. Industry believes that biotechnology will increase the usefulness of BCAs and is therefore encouraging cooperation with academic researchers and performing in-house research to advance the technology. Even so, BCAs will not replace chemicals in the foreseeable future, but will complement them and allow the development of improved integrated control measures.