HIV-1 natural viral suppressors: control of viral replication in the absence of therapy
- 19 February 2007
- journal article
- research article
- Published by Ovid Technologies (Wolters Kluwer Health) in AIDS
- Vol. 21 (4), 517-519
- https://doi.org/10.1097/qad.0b013e328013d9eb
Abstract
The objective of this study was to identify and define a cohort of HIV-1-infected individuals with the ability to suppress HIV-1 replication naturally (patients with undetectable viral loads for at least 2 years without antiretroviral drugs). Proviral DNA ranged from one to 74 copies/106 peripheral blood mononuclear cells, with the mean value lower by 1–2 logs than long-term non-progressors. This ability to control HIV-1 viral replication naturally has led us to refer to them as natural viral suppressors.Keywords
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