Anterior Segment OCT Imaging After Femtosecond Laser Cataract Surgery

Abstract
Original Article Zoltan Z. Nagy, MD, PhD, DSc; Tamás Filkorn, MD; Ágnes I. Takács, MD; Kinga Kránitz, MD; Tibor Juhasz, PhD, DSc; Eric Donnenfeld, MD; Michael C. Knorz, MD; Jorge L. Alio, MD, PhD To report the anterior segment imaging characteristics after femtosecond laser assisted cataract surgery. Cataract surgery was performed with the LenSx femtosecond laser (Alcon-LenSx Inc., Aliso Viejo, CA) in 40 eyes of 40 patients. The laser was programmed to perform a 4.5-mm capsulorhexis, a cross-pattern fragmentation of the nucleus, a 2.8-mm main incision, and a 1.0-mm side-port incision. The anterior segment was then analyzed using the Visante OCT anterior segment program (Zeiss-Meditec AG, Jena, Germany). The preoperatively set treatment parameters correlated well with the achieved results. For the capsulorhexis, the femtosecond laser cut was programmed to start 350 μm behind the anterior lens capsule and OCT measured 377 ± 55.3 μm. Nucleus fragmentation was programmed to start 750 μm in front of the posterior capsule and end 550 μm behind the anterior capsule, and OCT measured 794 ± 111 and 568 ± 147 μm, respectively. The diameter of the capsulorhexis measured by OCT was 4.54 ± 0.2 mm, compared to the 4.5 mm programmed. Anterior segment OCT imaging was able to detect the tissue changes within the lens after femtosecond laser capsulorhexis and nucleus fragmentation. The measured values correlated well with the planned treatment parameters. From the Department of Ophthalmology, Semmelweis University, Budapest, Hungary (ZZN, TF, AIT, KK, TJ); the Department of Ophthalmology, University of California–Irvine, Irvine, California (TJ); Ophthalmic Consultants of Long Island, Rockville Centre, New York (ED); Medical Faculty Mannheim of Heidelberg University, Mannheim, Germany (MCK); and the Department of Ophthalmology, Universidad Miguel Hernandez, Alicante, Spain (JLA). Drs. Nagy, Juhasz, Knorz, Donnenfeld, and Alio are consultants to Alcon-LenSx Inc. The remaining authors have no financial or proprietary interest in the materials presented herein. AUTHOR CONTRIBUTIONS Study concept and design (JLA, ED, TJ, KK, ZZN); data collection (JLA, TF, ZZN, AIT); analysis and interpretation of data (JLA, TF, MCK, ZZN); drafting of the manuscript (JLA, ZZN); critical revision of the manuscript (JLA, ED, TF, KK, MCK, AIT); statistical expertise (JLA); administrative, technical, or material support (TF, AIT); supervision (JLA, KK) Correspondence: Zoltan Z. Nagy, MD, PhD, DSc, Department of Ophthalmology, Semmelweis University, Mária u. 39, H-1085 Budapest, Hungary. E-mail: nz@szem1.sote.hu 10.3928/1081597X-20130117-05 To report the anterior segment imaging characteristics after femtosecond laser assisted cataract surgery. Cataract surgery was performed with the LenSx femtosecond laser (Alcon-LenSx Inc., Aliso Viejo, CA) in 40 eyes of 40 patients. The laser was programmed to perform a 4.5-mm capsulorhexis, a cross-pattern fragmentation of the nucleus, a 2.8-mm main incision, and a 1.0-mm side-port incision. The anterior segment was then analyzed using the Visante OCT anterior segment program (Zeiss-Meditec AG, Jena, Germany). The preoperatively set treatment parameters correlated well with the achieved results. For the capsulorhexis, the femtosecond laser cut was programmed to start 350 μm behind the anterior lens capsule and OCT measured 377 ± 55.3 μm. Nucleus fragmentation was programmed to start 750 μm in front of the posterior capsule and end 550 μm behind the anterior capsule, and OCT measured 794 ± 111 and 568 ± 147 μm, respectively. The diameter of the capsulorhexis measured by OCT was 4.54 ± 0.2 mm, compared to the 4.5 mm programmed. Anterior segment OCT imaging was able to detect the tissue changes within the lens after femtosecond laser capsulorhexis and nucleus fragmentation. The measured values correlated well with the planned treatment parameters. From the Department of Ophthalmology, Semmelweis University, Budapest, Hungary (ZZN, TF, AIT, KK, TJ); the Department of Ophthalmology, University of California–Irvine, Irvine, California (TJ); Ophthalmic Consultants of Long Island, Rockville Centre, New York (ED); Medical Faculty Mannheim of Heidelberg University, Mannheim, Germany (MCK); and the Department of Ophthalmology, Universidad Miguel Hernandez, Alicante, Spain (JLA). Drs. Nagy, Juhasz, Knorz, Donnenfeld, and Alio are consultants to Alcon-LenSx Inc. The remaining authors have no financial or proprietary interest in the materials presented herein. AUTHOR CONTRIBUTIONS Study concept and design (JLA, ED, TJ, KK, ZZN); data collection (JLA, TF, ZZN, AIT); analysis and interpretation of data (JLA, TF, MCK, ZZN); drafting of the manuscript (JLA, ZZN); critical revision of the manuscript (JLA, ED, TF, KK, MCK, AIT); statistical expertise (JLA); administrative, technical, or material support (TF, AIT); supervision (JLA, KK) Correspondence: Zoltan Z. Nagy, MD, PhD, DSc, Department of Ophthalmology, Semmelweis University, Mária u. 39, H-1085 Budapest, Hungary. E-mail: nz@szem1.sote.hu