Viral and Inflammatory Triggers of Neurodegenerative Diseases
- 15 February 2012
- journal article
- review article
- Published by American Association for the Advancement of Science (AAAS) in Science Translational Medicine
- Vol. 4 (121), 121ps3
- https://doi.org/10.1126/scitranslmed.3003492
Abstract
Immune pathways and cytokines induced by viral infections can render neurons vulnerable to subsequent degeneration and may serve as therapeutic targets for neuroprotection.Keywords
This publication has 52 references indexed in Scilit:
- Solvent exposures and parkinson disease risk in twinsAnnals of Neurology, 2011
- A Prospective Study of Bowel Movement Frequency and Risk of Parkinson's DiseaseAmerican Journal of Epidemiology, 2011
- Current understanding of HIV-associated neurocognitive disorders pathogenesisCurrent Opinion in Neurology, 2011
- Parkinson’s disease-linked LRRK2 is expressed in circulating and tissue immune cells and upregulated following recognition of microbial structuresJournal of Neural Transmission, 2011
- Common genetic variation in the HLA region is associated with late-onset sporadic Parkinson's diseaseNature Genetics, 2010
- Increased Expression of α-Synuclein Reduces Neurotransmitter Release by Inhibiting Synaptic Vesicle Reclustering after EndocytosisNeuron, 2010
- Highly pathogenic H5N1 influenza virus can enter the central nervous system and induce neuroinflammation and neurodegenerationProceedings of the National Academy of Sciences of the United States of America, 2009
- A novel pathogenic pathway of immune activation detectable before clinical onset in Huntington's diseaseThe Journal of Experimental Medicine, 2008
- Central and systemic IL-1 exacerbates neurodegeneration and motor symptoms in a model of Parkinson's diseaseBrain, 2008
- Toll-like receptor 8 functions as a negative regulator of neurite outgrowth and inducer of neuronal apoptosisThe Journal of cell biology, 2006