Cyanobacterial microcystin‐LR is a potent and specific inhibitor of protein phosphatases 1 and 2A from both mammals and higher plants
Open Access
- 21 May 1990
- journal article
- research article
- Published by Wiley in FEBS Letters
- Vol. 264 (2), 187-192
- https://doi.org/10.1016/0014-5793(90)80245-e
Abstract
The cyclic heptapeptide, microcystin‐LR, inhibits protein phosphatases 1 (PP1) and 2A (PP2A) with K i, values below 0.1 nM. Protein phosphatase 2B is inhibited 1000‐fold less potently, while six othe...Keywords
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