Metal Infiltration into Biomaterials by ALD and CVD: A Comparative Study
- 21 February 2011
- journal article
- research article
- Published by Wiley in Chemphyschem
- Vol. 12 (4), 791-798
- https://doi.org/10.1002/cphc.201000923
Abstract
Atomic layer deposition (ALD) is a subset of chemical vapor deposition (CVD) and both use very similar chemistry. Recently, it has been reported that ALD has the potential to realize a new design paradigm of bioinorganic materials through metal infiltration, which in nature has been employed as a hardening strategy for many tissues in diverse biological organisms. Herein, using a spider dragline silk and a collagen membrane as targets, we have performed a comparative study to elucidate the difference of the metal infiltration effect by ALD and CVD. From the comparison of mechanical properties, concentration of the infiltrated metal, and structural changes induced by the infiltrated metal, it has been proven that the metal can effectively infiltrate biomaterials by ALD and the infiltrated metal leads to highly improved mechanical properties accompanied by substantial changes in the protein structures, whereas CVD is less effective.This publication has 37 references indexed in Scilit:
- Chemical Infiltration during Atomic Layer Deposition: Metalation of Porphyrins as Model SubstratesAngewandte Chemie, 2009
- Nanomechanics of collagen fibrils under varying cross-link densities: Atomistic and continuum studiesJournal of the Mechanical Behavior of Biomedical Materials, 2008
- Critical role of zinc in hardening of Nereis jawsJournal of Experimental Biology, 2006
- Nature designs tough collagen: Explaining the nanostructure of collagen fibrilsProceedings of the National Academy of Sciences of the United States of America, 2006
- Microfibrillar structure of type I collagen in situProceedings of the National Academy of Sciences of the United States of America, 2006
- Atomic Layer Deposition Chemistry: Recent Developments and Future ChallengesAngewandte Chemie-International Edition, 2003
- Single molecule force spectroscopy of spectrin repeats: low unfolding forces in helix bundlesJournal of Molecular Biology, 1999
- Chain conformation in the collagen moleculeJournal of Molecular Biology, 1979
- A low-viscosity epoxy resin embedding medium for electron microscopyJournal of Ultrastructure Research, 1969
- The molecular structure of collagenJournal of Molecular Biology, 1961