Activity of a selective inhibitor of nuclear export, selinexor (KPT-330), against AML-initiating cells engrafted into immunosuppressed NSG mice
- 23 July 2015
- journal article
- research article
- Published by Springer Science and Business Media LLC in Leukemia
- Vol. 30 (1)
- https://doi.org/10.1038/leu.2015.194
Abstract
No abstract availableThis publication has 42 references indexed in Scilit:
- BH3 profiling – Measuring integrated function of the mitochondrial apoptotic pathway to predict cell fate decisionsCancer Letters, 2013
- Antileukemic activity of nuclear export inhibitors that spare normal hematopoietic cellsLeukemia, 2012
- Prognostic Relevance of Integrated Genetic Profiling in Acute Myeloid LeukemiaThe New England Journal of Medicine, 2012
- Ran-dependent nuclear export mediators: a structural perspectiveThe EMBO Journal, 2011
- Recognition of nuclear targeting signals by Karyopherin-β proteinsCurrent Opinion in Structural Biology, 2010
- Heightened mitochondrial priming is the basis for apoptotic hypersensitivity of CD4+CD8+thymocytesProceedings of the National Academy of Sciences of the United States of America, 2010
- An allosteric mechanism to displace nuclear export cargo from CRM1 and RanGTP by RanBP1The EMBO Journal, 2010
- Structural basis for assembly and disassembly of the CRM1 nuclear export complexNature Structural & Molecular Biology, 2009
- Structural basis for leucine-rich nuclear export signal recognition by CRM1Nature, 2009
- Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cellNature Medicine, 1997