Clinicopathologic Features and Prognostic Factors of Primary Extranodal Non-Hodgkin’s Lymphomas in Turkey
- 1 December 1999
- journal article
- cancer clinical-trials
- Published by Ovid Technologies (Wolters Kluwer Health) in American Journal of Clinical Oncology
- Vol. 22 (6), 587-92
- https://doi.org/10.1097/00000421-199912000-00009
Abstract
Clinical, histopathologic, and prognostic features of 114 patients with primary extranodal non-Hodgkin’s lymphoma were evaluated. Median age of the patients was 48 (range, 15–76) and the ratio of male/female was 55/59. Thirty-seven patients had stage 1, 55 patients stage II, 6 patients stage III, and 16 patients stage IV. The most common sites of primary extranodal non-Hodgkin’s lymphoma were the gastrointestinal (GI) tract and head–neck region. Stomach (66%) and tonsils (33%) were the most frequently involved organ in GI tract and head–neck region, respectively. Eighty percent of patients had intermediate or high-grade lymphomas, 20% had low-grade subtypes. Complete remission was achieved in 83% of all patients with chemotherapy ± radiotherapy ± surgery. Overall and disease-free survival at 5 years were 63% and 59%, respectively. In conclusion, clinical and histopathologic characteristics and prognosis of our cases with primary extranodal non-Hodgkin’s lymphoma were usually similar to those of the cases in Western countries with some differences in the incidence of some specific primary extranodal non-Hodgkin’s lymphomas and in the histopathologic subtypes.Keywords
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