Fatal disseminated toxoplasmosis in a toxoplasma seropositive liver transplant recipient
Open Access
- 1 August 2002
- journal article
- other
- Published by BMJ in Journal of Clinical Pathology
- Vol. 55 (8), 637
- https://doi.org/10.1136/jcp.55.8.637
Abstract
Disseminated toxoplasmosis is a severe disease that occurs in immunocompromised patients but has been rarely reported after liver transplantation. We describe the first case of fatal disseminated toxoplasmosis in a toxoplasma seropositive liver transplant recipient with a documented lack of a rise in specific IgG. A 53 year old patient underwent liver transplantation because of decompensated alcoholic cirrhosis. The patient was treated with antithymocyte globulins and prednisolone. Tacrolimus was added and antithymocyte treatment stopped. Oral ganciclovir was given to prevent cytomegalovirus infection. On day 22, the patient developed fever with chills. Physical examination was normal and blood analysis revealed leucopenia (leucocytes, 700/mm3). Blood, urine, …Keywords
This publication has 9 references indexed in Scilit:
- Diagnosis of toxoplasmosis in bone marrow transplant recipients: comparison of PCR-based results and immunohistochemistryBone Marrow Transplantation, 2000
- Disseminated toxoplasmosis after liver transplantation: case report and review.1998
- Disseminated Toxoplasmosis After Liver Transplantation: Case Report and ReviewClinical Infectious Diseases, 1998
- Transmission of Toxoplasma gondii Infection by Liver TransplantationClinical Infectious Diseases, 1995
- Septic Shock Due to Toxoplasmosis in Patients Infected With the Human Immunodeficiency VirusChest, 1993
- Role of Bronchoalveolar Lavage in Diagnosis of Disseminated ToxoplasmosisClinical Infectious Diseases, 1991
- Disseminated toxoplasmosis in the compromised host. A report of five cases.1974
- Disseminated Toxoplasmosis in the Compromised HostArchives of Internal Medicine, 1974
- Disseminated toxoplasmosis in a liver transplant patient.1972