Ecdysones and synthetic analogs: Molting hormone activity and inhibitive effects on insect growth, metamorphosis and reproduction

Abstract

Five ecdysones and 19 ecdysone analogs were assessed for molting hormone activity in the house fly assay. When these 5β-steroids were further tested in the house fly, the confused flour beetle, the yellow fever mosquito, and the German cockroach, many of the compounds inhibited growth, development and/or reproduction. The relationship of structure to both the molting hormone and inhibitive activity of these compounds is discussed.