In vivo visualization of abdominal malignancies with acoustic radiation force elastography
- 19 December 2007
- journal article
- research article
- Published by IOP Publishing in Physics in Medicine & Biology
- Vol. 53 (1), 279-293
- https://doi.org/10.1088/0031-9155/53/1/020
Abstract
The utility of acoustic radiation force impulse (ARFI) imaging for real-time visualization of abdominal malignancies was investigated. Nine patients presenting with suspicious masses in the liver (n = 7) or kidney (n = 2) underwent combined sonography/ARFI imaging. Images were acquired of a total of 12 tumors in the nine patients. In all cases, boundary definition in ARFI images was improved or equivalent to boundary definition in B-mode images. Displacement contrast in ARFI images was superior to echo contrast in B-mode images for each tumor. The mean contrast for suspected hepatocellular carcinomas (HCCs) in B-mode images was 2.9 dB (range: 1.5-4.2) versus 7.5 dB (range: 3.1-11.9) in ARFI images, with all HCCs appearing more compliant than regional cirrhotic liver parenchyma. The mean contrast for metastases in B-mode images was 3.1 dB (range: 1.2-5.2) versus 9.3 dB (range: 5.7-13.9) in ARFI images, with all masses appearing less compliant than regional non-cirrhotic liver parenchyma. ARFI image contrast (10.4 dB) was superior to B-mode contrast (0.9 dB) for a renal mass. To our knowledge, we present the first in vivo images of abdominal malignancies in humans acquired with the ARFI method or any other technique of imaging tissue elasticity.Keywords
This publication has 62 references indexed in Scilit:
- The Impact of Physiological Motion on Tissue Tracking During Radiation Force ImagingJapanese Journal of Clinical Oncology, 2007
- Liver ablation guidance with acoustic radiation force impulse imaging: challenges and opportunitiesPhysics in Medicine & Biology, 2006
- Noninvasive assessment of liver fibrosis by measurement of stiffness in patients with chronic hepatitis CHepatology, 2004
- Three-Dimensional Assessment of MRI-Guided Percutaneous Cryotherapy of Liver MetastasesAmerican Journal of Roentgenology, 2004
- Feasibility of applying ultrasound strain imaging to detect renal transplant chronic allograft nephropathyKidney International, 2004
- Screening for hepatocellular carcinoma: survival benefit and cost-effectivenessAnnals of Oncology, 2003
- MR Elastography of Breast Cancer: Preliminary ResultsAmerican Journal of Roentgenology, 2002
- Hepatocellular carcinomaJournal of Hepatology, 2000
- Renal Cell CarcinomaUrologia Internationalis, 1999
- The acoustic radiation forceAmerican Journal of Physics, 1984