Unexplained mortality differences between septic shock trials: a systematic analysis of population characteristics and control-group mortality rates
Open Access
- 15 March 2018
- journal article
- review article
- Published by Springer Science and Business Media LLC in Intensive Care Medicine
- Vol. 44 (3), 311-322
- https://doi.org/10.1007/s00134-018-5134-8
Abstract
Although the definition of septic shock has been standardized, some variation in mortality rates among clinical trials is expected. Insights into the sources of heterogeneity may influence the design and interpretation of septic shock studies. We set out to identify inclusion criteria and baseline characteristics associated with between-trial differences in control group mortality rates.This publication has 98 references indexed in Scilit:
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