Meniscal T1rho and T2 measured with 3.0T MRI increases directly after running a marathon
Open Access
- 30 October 2010
- journal article
- research article
- Published by Springer Science and Business Media LLC in Skeletal Radiology
- Vol. 40 (6), 725-735
- https://doi.org/10.1007/s00256-010-1058-2
Abstract
To prospectively evaluate changes in T1rho and T2 relaxation time in the meniscus using 3.0 T MRI in asymptomatic knees of marathon runners and to compare these findings with those of age-matched healthy subjects. Thirteen marathon runners underwent 3.0 T MRI including T1rho and T2 mapping sequences before, 48–72 h after, and 3 months after competition. Ten controls were examined at baseline and after 3 months. All images were analyzed by two musculoskeletal radiologists identifying and grading cartilage, meniscal, ligamentous. and other knee abnormalities with WORMS scores. Meniscal segmentation was performed to generate T1rho and T2 maps in six compartments. No differences in morphological knee abnormalities were found before and after the marathon. However, all marathon runners showed a significant increase in T1rho and T2 values after competition in all meniscus compartments (p < 0.0001), which may indicate changes in the biochemical composition of meniscal tissue. While T2 values decreased after 3 months T1rho values remained at a high level, indicating persisting changes in the meniscal matrix composition after a marathon. T2 values in menisci have the potential to be used as biomarkers for identifying reversible meniscus matrix changes indicating potential tissue damage. T1rho values need further study, but may be a valuable marker for diagnosing early, degenerative changes in the menisci following exercise.Keywords
This publication has 41 references indexed in Scilit:
- T1ρ relaxation time of the meniscus and its relationship with T1ρ of adjacent cartilage in knees with acute ACL injuries at 3TOsteoarthritis and Cartilage, 2009
- Meniscal Measurements of T1ρand T2 at MR Imaging in Healthy Subjects and Patients with OsteoarthritisRadiology, 2008
- In vivo T1ρ mapping in cartilage using 3D magnetization‐prepared angle‐modulated partitioned k‐space spoiled gradient echo snapshots (3D MAPSS)Magnetic Resonance in Medicine, 2008
- In vivo T1ρ and T2 mapping of articular cartilage in osteoarthritis of the knee using 3T MRIOsteoarthritis and Cartilage, 2007
- Delayed gadolinium‐enhanced magnetic resonance imaging of the meniscus: An index of meniscal tissue degeneration?Arthritis & Rheumatism, 2007
- Does marathon running cause acute lesions of the knee? Evaluation with magnetic resonance imagingEuropean Radiology, 2006
- Whole-Organ Magnetic Resonance Imaging Score (WORMS) of the knee in osteoarthritisOsteoarthritis and Cartilage, 2004
- Accurate assessment of precision errors: How to measure the reproducibility of bone densitometry techniquesOsteoporosis International, 1995
- Do asymptomatic marathon runners have an increased prevalence of meniscal abnormalities? An MR study of the knee in 23 volunteers.American Journal of Roentgenology, 1991
- The Effect of Running on the Pathogenesis of Osteoarthritis of the Hips and KneesPublished by Ovid Technologies (Wolters Kluwer Health) ,1985