Both myo-inositol to chiro-inositol epimerase activities and chiro-inositol to myo-inositol ratios are decreased in tissues of GK type 2 diabetic rats compared to Wistar controls
- 10 May 2002
- journal article
- research article
- Published by Elsevier BV in Biochemical and Biophysical Research Communications
- Vol. 293 (3), 1092-1098
- https://doi.org/10.1016/s0006-291x(02)00313-3
Abstract
No abstract availableKeywords
This publication has 15 references indexed in Scilit:
- D-Chiro-Inositol in Insulin Action and Insulin Resistance - Old-Fashioned Biochemistry Still at WorkIUBMB Life, 2001
- Chronic Activation of Protein Kinase C in Soleus Muscles and Other Tissues of Insulin-Resistant Type II diabetic Goto-Kakizaki (GK), Obese/Aged, and Obese/Zucker Rats: A Mechanism For Inhibiting Glycogen SynthesisDiabetes, 1996
- Urinary chiro-Inositol Excretion is an Index Marker of Insulin Sensitivity in Japanese Type II DiabetesDiabetes Care, 1994
- Insulin-induced activation of glycerol-3-phosphate acyltransferase by a chiro-inositol-containing insulin mediator is defective in adipocytes of insulin-resistant, type II diabetic, Goto-Kakizaki rats.Proceedings of the National Academy of Sciences of the United States of America, 1994
- Impaired skeletal muscle glycogen synthase activation by insulin in the Goto-Kakizaki (G/K) ratDiabetologia, 1994
- Insulin stimulates the biosynthesis of chiro-inositol-containing phospholipids in a rat fibroblast line expressing the human insulin receptor.Proceedings of the National Academy of Sciences of the United States of America, 1993
- chiro-inositol deficiency and insulin resistance: a comparison of the chiro-inositol- and the myo-inositol-containing insulin mediators isolated from urine, hemodialysate, and muscle of control and type II diabetic subjects.Proceedings of the National Academy of Sciences, 1993
- Low Urinarychiro-Inositol Excretion in Non-Insulin-Dependent Diabetes MellitusNew England Journal of Medicine, 1990
- Rat liver insulin mediator which stimulates pyruvate dehydrogenase phosphatase contains galactosamine and D-chiroinositolBiochemical and Biophysical Research Communications, 1988
- Identification and partial characterization of inositol; NAD+ epimerase and inosose: NAD(P)H reductase from the fat body of the American cockroach, Periplaneta americanaBiochemistry, 1973