Colorectal Cancer Manifesting with Metastasis to Prolactinoma: Report of a Case Involving Symptoms Mimicking Pituitary Apoplexy
Open Access
- 1 January 2014
- journal article
- case report
- Published by Japanese Society of Internal Medicine in Internal Medicine
- Vol. 53 (17), 1965-1969
- https://doi.org/10.2169/internalmedicine.53.2353
Abstract
Pituitary metastasis is an uncommon first presentation of systemic malignancy. The most common presenting symptom of pituitary metastasis is diabetes insipidus reflecting involvement of the stalk and/or posterior pituitary. We herein present a unique case of the coexistence of both a functioning pituitary adenoma (prolactinoma) and pituitary metastasis of advanced colorectal cancer with pituitary apoplexy as the first manifestation of underlying malignancy. The present case emphasizes the need to consider pituitary metastasis as a differential diagnosis in patients presenting with pituitary lesions and be aware that tumor-to-tumor metastasis can occur unexpectedly in those with pituitary metastases.Keywords
This publication has 9 references indexed in Scilit:
- Pituitary Apoplexy Presenting Atypical Time Course of Ophthalmic SymptomsThe Tohoku Journal of Experimental Medicine, 2012
- UK guidelines for the management of pituitary apoplexyClinical Endocrinology, 2010
- Metastases to the pituitary glandNeurosurgical Focus, 2004
- Metastases to the Pituitary GlandThe Endocrinologist, 2002
- Metastatic adenocarcinoma to a pituitary adenomaAnnals of Diagnostic Pathology, 2001
- Symptomatic pituitary metastasesJournal of Neurosurgery, 1998
- Metastatic prostatic adenocarcinoma presenting as complete ophthalmoplegia from pituitary apoplexy.British Journal of Ophthalmology, 1994
- Metastatic carcinoma to pituitary adenoma report of two casesSurgical Neurology, 1988
- Clinicopathologic review of 88 cases of carcinoma metastatic to the pituitary glandCancer, 1975