Detection and distribution of aluminium in bone.
Open Access
- 1 February 1984
- journal article
- research article
- Published by BMJ in Journal of Clinical Pathology
- Vol. 37 (2), 136-142
- https://doi.org/10.1136/jcp.37.2.136
Abstract
The distribution of aluminium has been investigated using a new histochemical technique in transiliac bone biopsy specimens from 20 patients with aluminium related bone disease and 17 with other metabolic bone diseases. The method, which employs solochrome azurine at acid pH (acid solochrome azurine), showed a wider distribution of aluminium within cortical and trabecular bone than other histochemical techniques. The results compared well with atomic absorption spectrophotometric analysis of these biopsy specimens. Wavelength dispersive electron probe analysis of serial sections validated the procedure. The method has certain advantages over both these analytical techniques.Keywords
This publication has 6 references indexed in Scilit:
- Treatment of fracturing renal osteodystrophy by desferrioxamine.1983
- Localisation of aluminium by histochemical and electron probe x-ray microanalytical techniques in bone tissue of cases of renal osteodystrophy.Journal of Clinical Pathology, 1982
- Haemodialysis related osteomalacia: a staining method to demonstrate aluminiumJournal of Clinical Pathology, 1981
- Hemodialysis encephalopathy with osteomalacic fractures and muscle weaknessKidney International, 1980
- HISTOPATHOLOGY OF RENAL OSTEODYSTROPHY WITH PARTICULAR REFERENCE TO THE EFFECTS OF lα‐HYDROXYVITAMIN D3 IN PATIENTS TREATED BY LONG‐TERM HAEMODIALYSISClinical Endocrinology, 1977
- A Simple Method of Defining Osteoid in Undecalcified SectionsJournal of Clinical Pathology, 1957