A Prospective Evaluation of the Charlson Comorbidity Index for Use in Long‐Term Care Patients
- 1 April 2002
- journal article
- research article
- Published by Wiley in Journal of the American Geriatrics Society
- Vol. 50 (4), 740-745
- https://doi.org/10.1046/j.1532-5415.2002.50172.x
Abstract
OBJECTIVES: Because of the high prevalence of coexisting medical conditions in frail older adults, clinical investigators often need to adjust for comorbidity when assessing the effect of long‐term care (LTC) on patient outcomes. This study examined the prognostic value of the Charlson Comorbidity Index (CCI) in predicting 3‐year mortality and functional decline in the LTC setting and compared its prognostic value to that of two data‐derived comorbidity indices. DESIGN: Longitudinal cohort study. SETTING: Eighty‐eight residential care facilities from Quebec, Canada. PARTICIPANTS: Two hundred ninety‐one dependent older adults aged 65 and older. MEASUREMENTS: Subjects' functional abilities were assessed at baseline and 3 years later with the revised version of the Functional Autonomy Measurement System (SMAF). Comorbidity data and the exact date of death for those who had died were collected retrospectively from the subjects' medical files. Subjects were classified as functional decliners if they died or gained 5 points or more on the SMAF between the two assessments. RESULTS: Multivariate Cox and logistic regressions were used to derive two new comorbidity indices, one for predicting mortality and the other for identifying functional decliners. Although the CCI performed well in predicting these two outcomes, its performance was generally inferior to that of the two newly proposed indices. CONCLUSIONS: Findings suggest that the CCI can be improved upon when used to measure comorbidity in LTC patients. J Am Geriatr Soc 50:740–745, 2002.Keywords
This publication has 36 references indexed in Scilit:
- The Performance of Different Lookback Periods and Sources of Information for Charlson Comorbidity Adjustment in Medicare ClaimsMedical Care, 1999
- Chronic Comorbidity and Outcomes of Hospital Care: Length of Stay, Mortality, and Readmission at 30 and 365 DaysJournal of Clinical Epidemiology, 1999
- Functional status outcomes for assessment of quality in long-term careInternational Journal for Quality in Health Care, 1999
- Special FeatureTopics in Geriatric Rehabilitation, 1998
- Assessing the impact of comorbidity in the older populationAnnals of Epidemiology, 1996
- Validation of a combined comorbidity indexJournal of Clinical Epidemiology, 1994
- Further evidence concerning the use of a clinical comorbidity index with ICD-9-CM administrative dataJournal of Clinical Epidemiology, 1993
- A note on a general definition of the coefficient of determinationBiometrika, 1991
- THE FUNCTIONAL AUTONOMY MEASUREMENT SYSTEM (SMAF): DESCRIPTION AND VALIDATION OF AN INSTRUMENT FOR THE MEASUREMENT OF HANDICAPSAge and Ageing, 1988
- A new method of classifying prognostic comorbidity in longitudinal studies: Development and validationJournal of Chronic Diseases, 1987