Molecular Photoacoustic Tomography with Colloidal Nanobeacons
- 19 May 2009
- journal article
- research article
- Published by Wiley in Angewandte Chemie
- Vol. 48 (23), 4170-4173
- https://doi.org/10.1002/anie.200805947
Abstract
Spotting clots: Vascularly constrained colloidal gold nanobeacons (GNBs; see picture) can be used as exogenous photoacoustic contrast agents for the targeted detection of fibrin, a major biochemical feature of thrombus. Fibrin‐targeted GNBs provide a more than tenfold signal enhancement in photoacoustic tomography in the near‐IR wavelength window, indicating their potential for diagnostic imaging.This publication has 23 references indexed in Scilit:
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